On February 13, 2025, Robert F. Kennedy Jr. was confirmed as Secretary of Health and Human Services (HHS) by the United States Senate with a vote of 52-48.

The confirmation primarily adhered to party lines, as all Democrats and one Republican, Senate Minority Leader Mitch McConnell, opposed the nomination due to Kennedy's previous remarks concerning vaccine safety.

At 71, Kennedy is an environmental attorney known for his outspoken criticism of vaccines and has led the nonprofit Children’s Health Defense, which has contested vaccine policies and advocated alternative health viewpoints.

His nomination by President Donald Trump encountered substantial resistance from public health specialists and even some members of his own family.

During the confirmation hearings, Kennedy reassured lawmakers of his commitment to evidence-based health policies and promised to hold regular oversight meetings with the Senate.

Nonetheless, critics continued to express concerns over his background of disseminating medical misinformation.

Family resistance to his nomination was particularly striking, with his cousin, U.S. Ambassador to Australia Caroline Kennedy, labeling him a 'predator' and vocally opposing his appointment.

Other relatives within the Kennedy family also distanced themselves from his views on public health.

As Secretary of HHS, Kennedy will manage agencies such as the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC), playing a pivotal role in shaping health policy in the United States.

His leadership is anticipated to impact federal health initiatives and vaccine programs amidst ongoing public discourse.